Adverse effects most commonly reported: headache, flushing, and indigestion. There may be visual disturbances, dizziness, and nasal congestion. Diarrhoea, vomiting, swelling of the eyelids, pain and redness of the eyes, nose bleeding, muscle pain, back pain, skin rashes, urinary-tract infection, temporally loss of consciousness, cerebrovascular bleeding, and transient ischaemic attack. Prolonged erection has also occurred. There have also been reports of serious cardiovascular events, including sudden cardiac death, hence all patients of hyper tension are warned not to use this drug. In erectile dysfunction the usual dose is sildenafil 50 mg about one hour before sexual intercourse. The dose may be increased or decreased depending on response. The maximum recommended dose is 100 mg, and sildenafil should not be taken more than once in 24 hours.
Description Adverse Effects Adverse effects most commonly reported with sildenafil are headache, flushing,and dyspepsia. Also common are visual disturbances such as blurred vision, photophobia, chromatopsia, cyanopsia, eye irritation, pain and redness of the eyes. Retinal haemorrhage has occurred, and non-arteritic anterior ischaemic optic neuropathy (NAION) causing permanent loss of vision has been reported rarely. Other common adverse effects include dizziness, insomnia, anxiety, vertigo, epistaxis, nasal congestion,pyrexia, and gastrointestinal disturbances such as diarrhoea and vomiting. Priapism can occur. Other adverse effects include skin rashes, erythema, alopecia, limb and/or back pain, myalgia, facial oedema, fluid retention,paraesthesia, and urinary-tract infection. Dyspnoea, cough, rhinitis, sinusitis, bronchitis, and cellulitis can occur. Sudden decrease or loss of hearing has been reported. Other reported effects include anaemia, leucopenia, gynaecomastia, urinary frequency or incontinence, haematuria, and seizures. Cerebrovascular haemorrhage and transient ischaemic attacks have occurred. There have also been reports of palpitations, syncope, hypertension, hypotension, and serious cardiovascular events including myocardial infarction, arrhythmias, tachycardia, unstable angina, and sudden cardiac death